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Sermorelin is a synthetic growth hormone releasing peptide that is often used by athletes, bodybuilders and individuals seeking to support anti-aging protocols. Because it comes in a lyophilised powder form, the first step before any injection is reconstitution with sterile water or bacteriostatic solution. Proper reconstitution not only guarantees accurate dosing but also preserves potency and safety.
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When you have purchased a vial of Sermorelin (typically 2 mg in a 1 ml ampoule), the next step is to decide how much water to add so that each millilitre contains the desired dose. A common practice is to reconstitute with 0.5 to 1.0 ml of sterile water, which gives you either a 4 mg/ml or 2 mg/ml concentration respectively.
The following table shows typical reconstitution volumes and resulting concentrations for standard vial sizes:
Vial Size (mg) Reconstitution Volume (ml) Concentration (mg/ml)
1.0 0.5 2.0
1.0 1.0 1.0
2.0 1.0 2.0
2.0 2.0 1.0
Once you have a known concentration, calculating the daily dose is straightforward: divide the desired milligram amount by the concentration to obtain the volume in microlitres or millilitres that should be drawn into a syringe.
Example: If you reconstitute 2 mg of Sermorelin with 1 ml water (giving 2 mg/ml) and your protocol calls for 0.5 mg per day, you would withdraw 0.25 ml (250 µl) from the vial each day.
Dosage charts used by clinicians and experienced users often list recommended daily ranges:
Low dose: 0.1 to 0.3 mg per day
Moderate dose: 0.4 to 0.6 mg per day
High dose: 0.7 to 1.0 mg per day
These ranges are tailored for age, body weight, and specific goals such as muscle growth or hormone replacement therapy. Always consult a healthcare professional before choosing a dose.
Tips for Successful Reconstitution
Sterile technique
Work in a clean area free of dust or microbes. Use gloves, a clean surface, and wipe the vial caps with alcohol before opening.
Use a sterile syringe
A 3 ml syringe with a 27-gauge needle is ideal for adding water to the vial. This gauge is fine enough to minimise tissue trauma but robust enough to handle the small volumes.
Gentle mixing
After adding the water, gently swirl or roll the vial between your hands. Avoid vigorous shaking