Sermorelin and ipamorelin are two synthetic peptides used to stimulate growth hormone release, while tesamorelin is another peptide in the same family with a slightly different profile. All three act by mimicking natural growth hormone releasing hormone (GHRH) or its analogues, but they differ in potency, duration of action, side-effect profile, and clinical applications.
Tesamorelin vs Sermorelin vs Ipamorelin
The first distinction lies in their molecular structure. Tesamorelin is a modified form of GHRH that contains 44 amino acids and has a longer half-life than sermorelin or ipamorelin. sermorelin ipamorelin before and after, on the other hand, is a shorter peptide consisting of 29 amino acids that closely resembles the first nine residues of native GHRH