There are diets that stimulate the secretion of GLP-1 from the gut. These data suggest that while free fatty acids result in an increase in unfolded protein accumulation, ColonBroom supplement there is an insufficient or effective level of GRP78 to abate the unfolded protein response. GLP-1 reduces the free fatty acid burden in human cells. In one way or another each of these fatty acid reservoirs is a consequence of a diet high in sugar (e.g. high fructose corn syrup) or fatty acids that are highly saturated or have an all trans- structure. We demonstrated here that CHOP levels were increased in hepatocytes that showed high steatosis with either of the fatty acid types. NAFLD refers to the spectrum of liver diseases in which steatosis can, in some humans, ColonBroom progress to more significant pathology including NASH and NASH-related cirrhosis. Immunohistochemical staining of liver sections for GRP78 and CHOP in mice given ALIOS diet and liraglutide suggest that GLP-1 analogs impart a strong affect in liver