Manufacture of Soft Gelatin Capsules: An Overview

Soft Gelatin Capsules, also known as softgels, are one of the most popular forms of dietary supplements and medications. They are easy to swallow and offer a convenient way to take various active ingredients, such as vitamins, minerals, and oils. The soft gelatine shell of these capsules is made from a combination of gelatin, glycerin, and water, and provides an effective barrier against light, moisture, and air.

Vadodara, the cultural capital of Gujarat, is home to a thriving pharmaceutical industry and many companies are involved in the manufacture of soft gelatin capsules. In this blog post, we will take a look at the process of manufacturing soft gelatin capsules and answer some of the frequently asked questions about this process.

Image description

Steps in the Manufacture of Soft Gelatin Capsules

  1. Preparation of the Gelatin Solution: The first step in the manufacture of soft gelatin capsules is the preparation of the gelatin solution. Gelatin, glycerin, and water are mixed in the correct proportions to form a homogeneous solution.
  2. Drying of the Gelatin Solution: The gelatin solution is then dried to form a thin film that will be used to form the capsule shell. This is typically done in a drying oven.
  3. Cutting of the Film into Circles: The dried gelatin film is then cut into circles using a special machine.
  4. Forming of the Capsule Shells: The circles of gelatin film are then fed into a machine that forms the capsule shells. The machine uses heat and pressure to mold the gelatin film into the desired shape.
  5. Filling of the Capsules: The next step is to fill the capsule shells with the active ingredients. This is typically done using a special filling machine.
  6. Sealing of the Capsules: The filled capsules are then sealed to prevent the active ingredients from spilling out. This is typically done using a special sealing machine.
  7. Quality Control: The final step in the manufacture of soft gelatin capsules is quality control. The capsules are thoroughly tested to ensure that they meet all the required quality standards.

What is the primary material used in the manufacture of soft gelatin capsules?
The primary material used in the manufacture of soft gelatin capsules is gelatin, which is derived from collagen, a protein found in animal bones and connective tissue.

What is the role of glycerin in the manufacture of soft gelatin capsules?
Glycerin is used in the manufacture of soft gelatin capsules as a plasticizer. It helps to keep the capsule shells soft and pliable.

What is the role of water in the manufacture of soft gelatin capsules?
Water is used in the manufacture of soft gelatin capsules to dissolve the gelatin and glycerin. It also helps to control the consistency of the gelatin solution.

What are the different types of filling machines used in the manufacture of soft gelatin capsules?
The different types of filling machines used in the manufacture of soft gelatin capsules include volumetric filling machines, gravity filling machines, and pressure filling machines.

What are the different types of sealing machines used in the manufacture of soft gelatin capsules?
The different types of sealing machines used in the manufacture of soft gelatin capsules include heat-sealing machines and ultrasonic sealing machines.

Edit
Pub: 10 Feb 2023 04:42 UTC
Views: 125