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Calculate degree of violation of a molecular clock (or DVMC) in a phylogeny. Sum-of-pairs is an accuracy metric for a multiple alignment relativeto a reference alignment. It is calculated by summing the correctlyaligned residue pairs over all pairs of sequences. Lower RCV values are thought to be desirable because they representa lower composition bias in an alignment. Statistically, RCV describesthe average variability in sequence composition among taxa.

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Pub: 10 Sep 2025 04:35 UTC

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