Niacin, or vitamin B3, is a water-soluble B vitamin found naturally in some foods, added to foods, and Neuro Surge Brain Support offered as a complement. The two commonest types of niacin in food and Neuro Surge Brain Support supplements are nicotinic acid and nicotinamide. The physique also can convert tryptophan-an amino acid-to nicotinamide. Niacin is water-soluble so that excess amounts the physique doesn't need are excreted within the urine. Niacin works in the physique as a coenzyme, with greater than four hundred enzymes dependent on it for numerous reactions. Niacin helps to convert nutrients into power, create cholesterol and fats, create and repair DNA, and exert antioxidant results. RDA: Niacin is measured in milligrams (mg) of niacin equivalents (NE). One NE equals 1 milligram of niacin or 60 mg of tryptophan. 16 mg NE for males, 14 mg NE for ladies, 18 mg NE for pregnant women, and 17 mg NE for lactating girls. UL: The Tolerable Upper Intake Level is the maximum daily intake unlikely to trigger dangerous effects on health.

For more than forty years, niacin in the form of nicotinic acid has been given to patients to treat a condition referred to as dyslipidemia, a major Neuro Surge Brain Support threat issue for cardiovascular diseases (CVD) such as coronary artery disease, coronary heart assault, and strokes. Bloodwork in somebody with dyslipidemia could show excessive total and LDL "bad" cholesterol ranges, low HDL "good" cholesterol, Neuro Surge Brain Support and elevated triglycerides. Nicotinic acid supplements contain excessive quantities, as much as 1,000-2,000 mg of niacin taken each day. Studies have shown that they'll improve HDL cholesterol and Neuro Surge Brain Support lower LDL cholesterol and triglycerides. However, negative uncomfortable side effects (skin flushing, stomach upset, diarrhea) usually accompany the supplements, resulting in poor compliance from patients. Clinical trials have not consistently proven that nicotinic acid leads to much less cardiovascular occasions or deaths from CVD. Though earlier clinical trials confirmed a discount in CVD occasions and deaths with niacin therapy, Neuro Surge Supplement two more recent massive clinical trials on CVD outcomes concluded in a different way.

Both were large randomized placebo-managed trials, following participants for as much as four years. Niacin supplements had been given (1,500-2,000 mg daily), alone in one trial and with a statin treatment in the other. Both trials concluded that taking niacin supplements didn't show profit. The niacin/statin trial did not present a discount in strokes, heart assault, or CVD deaths despite important improvements in HDL cholesterol and triglyceride ranges. The niacin supplement-only trial did not discover a reduction in CVD occasions and also famous a major improve in antagonistic reactions in contrast with the placebo group, including increased incidence of type 2 diabetes, gastrointestinal bleeding and ulcers, and diarrhea. A Cochrane overview of 23 randomized controlled trials on nicotinic acid supplements for the prevention of CVD events discovered that the supplements did not cut back overall deaths, CVD deaths, coronary heart assaults, and Neuro Surge Brain Support strokes, and was associated with adverse unintended effects. The results of these and different cardiovascular outcome trials led the U.

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Pub: 17 Dec 2025 21:00 UTC

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