Oxygen (O2) transport and hemostasis are central to human adaptation to stress/damage and to illness pathobiology. The interdisciplinary Center for Blood Oxygen Transport & Hemostasis (CBOTH) addresses basic, difficult questions related to blood O2 transport and hemostasis from a programs perspective, BloodVitals device with attention to human biology, physiology and therapeutics. Innovative study of O2 transport, hemostasis and key interacting biologic programs crosses conventional disciplines