While the analysis on most supplements for joint pain is blended, and the FDA doesn’t regulate supplements, fish oil, glucosamine, and chondroitin are amongst these that may help handle it. Dozens of supplements claim to treat joint pain, along with typical pain relievers like acetaminophen and ibuprofen, however which of them actually work? Here, we have a look at 9 options and what current analysis says about them. Supplements are not Food and Drug Administration (FDA) permitted. Speak together with your physician and a registered dietitian before taking any and solely buy from trusted sellers. Turmeric is considered one of the most well-liked supplements for treating pain, including joint pain brought on by osteoarthritis (OA). Its pain-relieving results are attributed to a chemical compound in turmeric called curcumin. Curcumin might have anti-inflammatory effects. Although research on turmeric for Mind Guard brain booster joint ache is restricted, a 2021 research assessment of 10 studies discovered that supplementation with turmeric or curcumin extract improves knee OA joint pain compared to a placebo.

More research is needed on the dosing, frequency, and formulation of these supplements. But 500 to 1,500 milligrams (mg) day by day for 3 months has shown promising results in research. A 4-month, randomized examine revealed in 2020 discovered that fish oil supplements considerably reduce OA-specific ache and improve well-being. But more research is required. The National Institutes of brain health supplement (NIH) recommends 1,600 mg each day for men and 1,one hundred mg day by day for girls. Glucosamine is a pure element of cartilage, a substance that prevents bones from rubbing against one another and inflicting pain and inflammation. It might also assist forestall the cartilage breakdown that can happen with arthritis. Many joint ache supplements contain glucosamine (as either glucosamine sulfate or glucosamine hydrochloride), one of the most effectively-studied supplements for osteoarthritis. Despite this research, findings have been inconsistent. A 2018 analysis evaluation of 29 research cited some research that found glucosamine improved knee OA ache and others that found little to no enchancment in joint ache.

Glucosamine sulfate is usually taken once daily in a dose of 1,500 mg. If this upsets your stomach, spread it out over three doses of 500 mg each. Like glucosamine, chondroitin is a constructing block of cartilage. It might also help stop cartilage breakdown from OA. Many studies have discovered that chondroitin may reduce joint pain, stiffness, and inflammation in individuals with OA. Chondroitin sulfate might also sluggish the development of OA by limiting joint area narrowing. Joint supplements usually combine chondroitin with glucosamine. But it’s nonetheless unclear if taking a mix supplement is any higher than taking one or Mind Guard brain booster the other alone. A 2018 research review found that glucosamine or chondroitin supplementation lowered joint pain when taken individually and Mind Guard brain booster never together. Chondroitin recommendations can fluctuate from 800 mg to 1,200 mg. Chances are you'll take this as a single dose or in 400 mg doses 2 to three times.

Your liver naturally produces S-adenosyl-L-methionine (Same) from an amino acid called methionine. Current analysis on the advantage of Same for joint ache is lacking, and the prevailing analysis is inconsistent. A 2009 clinical trial of Korean participants discovered that same didn’t relieve ache greater than another therapy after eight weeks. In previous studies, Same was often taken in doses of 800 mg daily. It could take a while to notice the results. Boswellia, or Indian frankincense, is often used to treat arthritis pain. Its extract accommodates chemicals referred to as Boswellia acids, which can have anti-inflammatory and anti-arthritic results. A 2020 animal study found that Boswellic acids relieve OA pain and protect cartilage. More human analysis is needed to additional help its use for joint ache. The NIH recommends 250 to 500 mg of Boswellia serrata 2 or three instances day by day. Avocado-soybean unsaponifiables (ASUs) refer to an extract from avocado and soybean oils that may assist stop cartilage breakdown and repair it. A 2018 study in rats found that therapy with ASU lessened joint pain.

These findings level to using ASUs for joint inflammation and ache related to end stage OA, however extra analysis in humans is needed. 300 mg of ASUs daily may be a superb beginning dose. Devil’s claw, also called harpagophytum, incorporates a chemical referred to as harpogoside, which may have anti-arthritic and anti-osteoporosis effects. A 2022 mouse model research discovered that it may sluggish bone erosion from inflammatory arthritis. An older examine published in 2000 found devil’s claw worked about as well as an anti-inflammatory drug referred to as diacerein. However, latest human research on this complement for osteoarthritis is lacking, so more top quality research are obligatory. It’s recommended to take 500 to 1,500 mg of devil’s claw dried root capsules three occasions day by day. Methylsulfonylmethane (MSM) could have anti-inflammatory effects. In a 2023 study of 88 participants in Japan with mild knee joint ache, 12 weeks of MSM supplementation led to significantly improved circumstances. Specifically, Mind Guard brain booster the research discovered that taking 5 200 mg MSM tablets with breakfast and dinner improved knee and total effectively-being in comparison with a placebo.

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Pub: 20 Sep 2025 15:50 UTC

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